Biomarkers · Liver & Nutritional
Albumin:Globulin Ratio (A/G)
Higher values carry lower risk. In NHANES 1999–2018 with linked mortality to 2019, each standard deviation is associated with a hazard ratio of 0.76. Reproduces in NHANES
NHANES, our fit with 95% CIPublished curve
Hazard ratios relative to each curve's own reference value, so the two curves need not cross 1 at the same point. The dotted vertical line marks the NHANES median.
NHANES hazard per SD0.7695% CI 0.74–0.78 · 48,307 adults, 7,024 deaths
Published hazard ratio0.75per SD (95% CI 0.28–0.49) · NHANES 2003-2018, adults with cardiovascular-kidney-metabolic (CKM) syndrome, mortality follow-up through 31 Dec 2019, median follow-up 8.33 years, 1745 all-cause deaths
Where people sit
Population percentiles (ratio) by sex and age band. Cycle or source as recorded in the catalogue.
| Sex | Age | 5th | 25th | Median | 75th | 95th | n | Cycle / source |
|---|---|---|---|---|---|---|---|---|
| All | 20-39 | 0.95 | 1.17 | 1.35 | 1.57 | 1.93 | 31,091 | Wang G, Li G, Wang P, … |
| All | 40-59 | 1.06 | 1.28 | 1.47 | 1.68 | 2.04 | 31,091 | Wang G, Li G, Wang P, … |
| All | 60+ | 1.18 | 1.42 | 1.60 | 1.81 | 2.17 | 31,091 | Wang G, Li G, Wang P, … |
| All | all | 1.06 | 1.28 | 1.47 | 1.68 | 2.04 | 31,091 | Wang G, Li G, Wang P, … |
| Men | all | 1.08 | 1.31 | 1.50 | 1.71 | 2.07 | 31,091 | Wang G, Li G, Wang P, … |
| Women | all | 1.03 | 1.25 | 1.44 | 1.65 | 2.02 | 31,091 | Wang G, Li G, Wang P, … |
Sources
- Hazard curve: Synthesized from mortality_association (HR=0.748057667883473 per_sd); per-SD log(HR)=0.290. Reported as per_unit HR=0.38 for all-cause mortality. HR of 0.38 (per 1-unit increase in AGR) after multivariable adjustment for age, sex, race, educa
- Wang G, Li G, Wang P, Zang M, Pu J. Association between albumin to globulin ratio and all-cause and cardiovascular mortality among individuals with cardiovascular-kidney-metabolic syndrome: results from NHANES 2003 to 2018. Front Nutr. 2025;12:1622590.
- Empirical curve: our Cox model with age and sex, NHANES 1999–2018 with linked mortality to 2019.