PFLPhysiological Fitness Landscape

Biomarkers · Inflammation

CD4:CD8 T-Cell Ratio

U-shaped: both low and high values carry risk. Not measured in our NHANES panel; the curve is synthesised from the published association.

Hazard ratio relative to the curve's reference value, as synthesised from the published association.

Published hazard ratio1.32top vs bottom third (95% CI 1.17–1.49) · NHANES III lymphocyte subset mortality linkage

Where people sit

Population percentiles (ratio) by sex and age band. Cycle or source as recorded in the catalogue.

SexAge5th25thMedian75th95thnCycle / source
All20-390.611.291.772.242.925,200Peto et al. 2017 (Mort…
All40-590.741.401.862.322.985,200Peto et al. 2017 (Mort…
All60+0.851.501.942.383.035,200Peto et al. 2017 (Mort…
Allall0.741.401.862.322.985,200Peto et al. 2017 (Mort…
Menall0.731.371.822.262.905,200Peto et al. 2017 (Mort…
Womenall0.751.431.902.373.055,200Peto et al. 2017 (Mort…