PFLPhysiological Fitness Landscape

Biomarkers · Metabolic

Serum Citrate

U-shaped: both low and high values carry risk. Not measured in our NHANES panel; the curve is synthesised from the published association.

Hazard ratio relative to the curve's reference value, as synthesised from the published association.

Published hazard ratio1.25top vs bottom third (95% CI 1.12–1.40) · ARIC metabolomics substudy

Where people sit

Population percentiles (mmol/L) by sex and age band. Cycle or source as recorded in the catalogue.

SexAge5th25thMedian75th95thnCycle / source
All20-390.040.070.100.120.155,100Peto et al. 2017 (Mort…
All40-590.050.090.110.140.175,100Peto et al. 2017 (Mort…
All60+0.070.110.130.160.195,100Peto et al. 2017 (Mort…
Allall0.050.090.110.140.175,100Peto et al. 2017 (Mort…
Menall0.060.090.120.140.185,100Peto et al. 2017 (Mort…
Womenall0.050.080.110.130.175,100Peto et al. 2017 (Mort…