Biomarkers · Bone & Mineral

C-Terminal Telopeptide of Type I Collagen (CTX)

Lower values carry lower risk. Not measured in our NHANES panel; the curve is synthesised from the published association.

Hazard ratio relative to the curve's reference value, as synthesised from the published association.

Published hazard ratio1.70top vs bottom third (95% CI 1.40–2.00) · Barasch E, Gottdiener JS, Aurigemma G, Kitzman DW, Han J, Kop WJ, Tracy RP. The relationship between serum markers of collagen turnover and cardiovascular outcome in the elderly: the Cardiovascular Health Study. Circ Heart Fail. 2011;4(6):733-739.

Where people sit

Population percentiles (ng/mL) by sex and age band. Cycle or source as recorded in the catalogue.

Sex	Age	5th	25th	Median	75th	95th	n	Cycle / source
All	20-39	0.03	0.15	0.23	0.31	0.43	880	Peto et al. 2017 (Mort…
All	40-59	0.05	0.17	0.25	0.33	0.45	880	Peto et al. 2017 (Mort…
All	60+	0.08	0.19	0.27	0.35	0.47	880	Peto et al. 2017 (Mort…
All	all	0.05	0.17	0.25	0.33	0.45	880	Peto et al. 2017 (Mort…
Men	20-39	0.04	0.15	0.23	0.32	0.43	880	Peto et al. 2017 (Mort…
Men	40-59	0.06	0.17	0.26	0.34	0.45	880	Peto et al. 2017 (Mort…
Men	60+	0.08	0.20	0.28	0.36	0.48	880	Peto et al. 2017 (Mort…
Men	all	0.06	0.17	0.26	0.34	0.45	880	Peto et al. 2017 (Mort…
Women	20-39	0.03	0.14	0.23	0.31	0.42	880	Peto et al. 2017 (Mort…
Women	40-59	0.05	0.16	0.24	0.33	0.44	880	Peto et al. 2017 (Mort…
Women	60+	0.07	0.19	0.27	0.35	0.46	880	Peto et al. 2017 (Mort…
Women	all	0.05	0.16	0.24	0.33	0.44	880	Peto et al. 2017 (Mort…

Sources

Hazard curve: Peto et al. 2017 (PMID 28858850) anchor; external_cohort_anchor
Barasch E, Gottdiener JS, Aurigemma G, Kitzman DW, Han J, Kop WJ, Tracy RP. The relationship between serum markers of collagen turnover and cardiovascular outcome in the elderly: the Cardiovascular Health Study. Circ Heart Fail. 2011;4(6):733-739.

Map C-Terminal Telopeptide of Type I Collagen (CTX) against another biomarker.