PFLPhysiological Fitness Landscape

Biomarkers · Endocrine

Estradiol (17beta-Estradiol)

U-shaped: both low and high values carry risk. Not measured in our NHANES panel; the curve is synthesised from the published association.

Hazard ratio relative to the curve's reference value, as synthesised from the published association.

Published hazard ratio1.29top vs bottom third (95% CI 1.14–1.46) · NHANES 2001-2012 reproductive hormone mortality linkage

Where people sit

Population percentiles (pg/mL) by sex and age band. Cycle or source as recorded in the catalogue.

SexAge5th25thMedian75th95thnCycle / source
All20-39-40.5262.81352063103,600Peto et al. 2017 (Mort…
All40-59-42.3649.11131762683,600Peto et al. 2017 (Mort…
All60+-11.9739.174.61101613,600Peto et al. 2017 (Mort…
Allall-39.8553.61181832773,600Peto et al. 2017 (Mort…
Menall6.8320.630.239.853.63,600Peto et al. 2017 (Mort…
Womenall13.81191922663713,600Peto et al. 2017 (Mort…