Biomarkers · Liver & Nutritional
FIB-4 Index (NAFLD Fibrosis Score)
Lower values carry lower risk. Not measured in our NHANES panel; the curve is synthesised from the published association.
Hazard ratio relative to the curve's reference value, as synthesised from the published association.
Published hazard ratio1.64top vs bottom quarter (95% CI 1.23–2.18) · Korean general population (adults without viral hepatitis), n=46,456, median follow-up 8.6 years
Where people sit
Population percentiles (index) by sex and age band. Cycle or source as recorded in the catalogue.
| Sex | Age | 5th | 25th | Median | 75th | 95th | n | Cycle / source |
|---|---|---|---|---|---|---|---|---|
| All | 20-39 | 0.29 | 0.45 | 0.60 | 0.81 | 1.24 | 75,666 | Sugiyama A, Kurisu A, … |
| All | 40-59 | 0.45 | 0.67 | 0.88 | 1.16 | 1.71 | 75,666 | Sugiyama A, Kurisu A, … |
| All | 60+ | 0.69 | 1.05 | 1.40 | 1.87 | 2.84 | 75,666 | Sugiyama A, Kurisu A, … |
| All | all | 0.47 | 0.75 | 1.05 | 1.46 | 2.36 | 75,666 | Sugiyama A, Kurisu A, … |
| Men | all | 0.48 | 0.77 | 1.07 | 1.48 | 2.38 | 75,666 | Sugiyama A, Kurisu A, … |
| Women | all | 0.45 | 0.73 | 1.03 | 1.44 | 2.35 | 75,666 | Sugiyama A, Kurisu A, … |
Sources
- Hazard curve: Synthesized from mortality_association (HR=1.64 quartile_extreme); per-SD log(HR)=0.386. Reported as threshold HR=1.64 for all-cause mortality. Fully adjusted HR for presumed advanced hepatic fibrosis (FIB-4 >= 2.67) vs below threshold. CV
- Seo YG, Polyzos SA, Park KH, Mantzoros CS. Fibrosis-4 Index Predicts Long-Term All-Cause, Cardiovascular and Liver-Related Mortality in the Adult Korean Population. Clinical Gastroenterology and Hepatology. 2023;21(13):3322-3335.
Map FIB-4 Index (NAFLD Fibrosis Score) against another biomarker.