Biomarkers · Vitamins & Endocrine
Serum Folate
Higher values carry lower risk. Not measured in our NHANES panel; the curve is synthesised from the published association.
Hazard ratio relative to the curve's reference value, as synthesised from the published association.
Published hazard ratio0.35per SD (95% CI 0.83–0.94) · NHANES III, n=12,862 U.S. adults (mean age 47.5 years), median follow-up 26.4 years, 5,299 deaths
Where people sit
Population percentiles (ng/mL) by sex and age band. Cycle or source as recorded in the catalogue.
| Sex | Age | 5th | 25th | Median | 75th | 95th | n | Cycle / source |
|---|---|---|---|---|---|---|---|---|
| All | 20-39 | 7.20 | 14.5 | 18.5 | 23.5 | 35.5 | 2,580 | 2017-2018 |
| All | 40-59 | 6.50 | 13.5 | 17.5 | 22.5 | 35.0 | 2,550 | 2017-2018 |
| All | 60+ | 6.00 | 12.8 | 16.5 | 21.5 | 34.0 | 2,670 | 2017-2018 |
| All | all | 6.50 | 13.5 | 17.5 | 22.5 | 35.0 | 7,800 | 2017-2018 |
| Men | all | 6.80 | 14.0 | 18.2 | 23.2 | 36.0 | 3,780 | 2017-2018 |
| Women | all | 6.20 | 13.0 | 16.8 | 21.8 | 34.0 | 4,020 | 2017-2018 |
Sources
- Hazard curve: Synthesized from mortality_association (HR=0.35055640914604685 per_sd); per-SD log(HR)=1.048. Reported as per_unit HR=0.88 for all-cause mortality. HR is per 1.0 ug/L increase in log-transformed serum folate (i.e., risk of death is 12% lower pe
- Zhao Y, Lv J, Liu Y, Hu H, Zhan H. Association between serum folate concentrations and all-cause mortality in U.S. adults: a cohort study based on National Health and Nutrition Examination Survey III. Frontiers in Nutrition. 2024.