Biomarkers · Cardiometabolic
Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)
Lower values carry lower risk. Not measured in our NHANES panel; the curve is synthesised from the published association.
Hazard ratio relative to the curve's reference value, as synthesised from the published association.
Published hazard ratio1.23top vs bottom third (95% CI 1.02–1.50) · Cardiovascular Health Study, n=3,949 adults aged >=65 years free of prevalent CVD at baseline; 665 CVD deaths; mean follow-up ~12.3 years (original cohort)
Where people sit
Population percentiles (nmol/min/mL) by sex and age band. Cycle or source as recorded in the catalogue.
| Sex | Age | 5th | 25th | Median | 75th | 95th | n | Cycle / source |
|---|---|---|---|---|---|---|---|---|
| All | 20-39 | 87.4 | 133 | 166 | 202 | 267 | 4,079 | US FDA. 510(k) Substan… |
| All | 40-59 | 95.0 | 145 | 180 | 220 | 290 | 4,079 | US FDA. 510(k) Substan… |
| All | 60+ | 104 | 158 | 196 | 240 | 316 | 4,079 | US FDA. 510(k) Substan… |
| All | all | 95.0 | 145 | 180 | 220 | 290 | 4,079 | US FDA. 510(k) Substan… |
| Men | all | 100 | 158 | 195 | 238 | 315 | 4,079 | US FDA. 510(k) Substan… |
| Women | all | 85.0 | 132 | 165 | 205 | 285 | 4,079 | US FDA. 510(k) Substan… |
Sources
- Hazard curve: Synthesized from mortality_association (HR=1.23 tertile_extreme); per-SD log(HR)=0.140. Reported as tertile_extreme HR=1.23 for cardiovascular mortality. Lp-PLA2 activity, highest vs lowest tertile, fully adjusted model, CVD death. A larg
- Jenny NS, Solomon C, Cushman M, Tracy RP, Nelson JJ, Psaty BM, Furberg CD. Lipoprotein-associated phospholipase A2 (Lp-PLA2) and risk of cardiovascular disease in older adults: results from the Cardiovascular Health Study. Atherosclerosis. 2010;209(2):528-532.
Map Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) against another biomarker.