PFLPhysiological Fitness Landscape

Biomarkers · Hematology

Absolute Neutrophil Count

Lower values carry lower risk. In NHANES 1999–2018 with linked mortality to 2019, each standard deviation is associated with a hazard ratio of 1.24. Reproduces in NHANES

NHANES, our fit with 95% CIPublished curve

Hazard ratios relative to each curve's own reference value, so the two curves need not cross 1 at the same point. The dotted vertical line marks the NHANES median.

NHANES hazard per SD1.2495% CI 1.21–1.27 · 48,954 adults, 7,151 deaths
Published hazard ratio1.32top vs bottom third (95% CI 1.20–1.45) · NHANES 1999-2010 mortality linkage (CBC panel)
Value of the measurement+0.022gain in C within age bands; rank 17 of 56 · all tests

Where people sit

Population percentiles (10^3 cells/uL) by sex and age band. Cycle or source as recorded in the catalogue.

SexAge5th25thMedian75th95thnCycle / source
All20-390.952.463.514.576.088,100Peto et al. 2017 (Mort…
All40-591.362.934.025.116.688,100Peto et al. 2017 (Mort…
All60+1.893.504.625.747.358,100Peto et al. 2017 (Mort…
Allall1.362.934.025.116.688,100Peto et al. 2017 (Mort…
Menall1.513.064.145.226.778,100Peto et al. 2017 (Mort…
Womenall1.202.793.905.016.608,100Peto et al. 2017 (Mort…

Sources

Map Absolute Neutrophil Count against another biomarker.