PFLPhysiological Fitness Landscape

Biomarkers · Anthropometric

Predicted Mass (UKB Impedance)

U-shaped: both low and high values carry risk. Not measured in our NHANES panel; the curve is synthesised from the published association.

Hazard ratio relative to the curve's reference value, as synthesised from the published association.

Published hazard ratio1.24top vs bottom third (95% CI 1.14–1.35) · UK Biobank prospective cohort (n=502,631)

Where people sit

Population percentiles (kg) by sex and age band. Cycle or source as recorded in the catalogue.

SexAge5th25thMedian75th95thnCycle / source
All20-3941.357.268.379.395.2450,000Peto et al. 2017 (Mort…
All40-5948.964.174.685.1100450,000Peto et al. 2017 (Mort…
All60+55.168.978.588.1102450,000Peto et al. 2017 (Mort…
Allall48.163.373.884.399.5450,000Peto et al. 2017 (Mort…
Menall64.576.584.993.2105450,000Peto et al. 2017 (Mort…
Womenall43.655.563.771.983.8450,000Peto et al. 2017 (Mort…