PFLPhysiological Fitness Landscape

Biomarkers · Cardiac & Hemodynamics

Pulse Pressure

Lower values carry lower risk. In NHANES 1999–2018 with linked mortality to 2019, each standard deviation is associated with a hazard ratio of 1.11. Reproduces in NHANES

NHANES, our fit with 95% CIPublished curve

Hazard ratios relative to each curve's own reference value, so the two curves need not cross 1 at the same point. The dotted vertical line marks the NHANES median.

NHANES hazard per SD1.1195% CI 1.08–1.13 · 49,318 adults, 7,264 deaths
Published hazard ratio1.40per SD (95% CI 1.34–1.46) · Weitzman D, Goldbourt U. The significance of various blood pressure indices for long-term stroke, coronary heart disease, and all-cause mortality in men: the Israeli Ischemic Heart Disease study. Stroke. 2006;37(2):358-362.
Value of the measurement+0.007gain in C within age bands; rank 47 of 56 · all tests
Across cohorts, HR per SD1.11NHANES 1.11 [1.08–1.13] · HRS 1.09 [1.07–1.12]

Where people sit

Population percentiles (mmHg) by sex and age band. Cycle or source as recorded in the catalogue.

SexAge5th25thMedian75th95thnCycle / source
All20-3924.733.840.246.655.79,611Peto et al. 2017 (Mort…
All40-5928.237.343.750.159.29,611Peto et al. 2017 (Mort…
All60+32.141.347.654.063.29,611Peto et al. 2017 (Mort…
Allall28.237.343.750.159.29,611Peto et al. 2017 (Mort…
Men20-3925.534.641.047.456.69,611Peto et al. 2017 (Mort…
Men40-5929.038.244.650.960.19,611Peto et al. 2017 (Mort…
Men60+33.042.248.655.064.19,611Peto et al. 2017 (Mort…
Menall29.038.244.650.960.19,611Peto et al. 2017 (Mort…
Women20-3923.933.039.445.854.99,611Peto et al. 2017 (Mort…
Women40-5927.336.542.849.258.49,611Peto et al. 2017 (Mort…
Women60+31.140.346.753.062.29,611Peto et al. 2017 (Mort…
Womenall27.336.542.849.258.49,611Peto et al. 2017 (Mort…

Sources