Biomarkers · Vitamins & Endocrine
Total Testosterone
Higher values carry lower risk. Not measured in our NHANES panel; the curve is synthesised from the published association.
Hazard ratio relative to the curve's reference value, as synthesised from the published association.
Published hazard ratio0.89top vs bottom quarter (95% CI 0.83–0.97) · Systematic review and dose-response meta-analysis of 53 prospective cohort study publications, n=359047 participants (community-dwelling and clinical cohorts of men and women)
Where people sit
Population percentiles (ng/dL) by sex and age band. Cycle or source as recorded in the catalogue.
| Sex | Age | 5th | 25th | Median | 75th | 95th | n | Cycle / source |
|---|---|---|---|---|---|---|---|---|
| All | 20-39 | 160 | 300 | 440 | 600 | 950 | 1,720 | 2017-2018 |
| All | 40-59 | 125 | 225 | 350 | 490 | 860 | 1,690 | 2017-2018 |
| All | 60+ | 90.0 | 175 | 280 | 410 | 720 | 1,790 | 2017-2018 |
| All | all | 120 | 220 | 340 | 480 | 850 | 5,200 | 2017-2018 |
| Men | all | 180 | 340 | 490 | 650 | 980 | 2,550 | 2017-2018 |
| Women | all | 60.0 | 130 | 220 | 340 | 580 | 2,650 | 2017-2018 |
Sources
- Hazard curve: Synthesized from mortality_association (HR=0.89 quartile_extreme); per-SD log(HR)=0.091. Reported as per_unit HR=0.89 for all-cause mortality. Dose-response analysis found a significant U-shaped association between total testosterone and a
- Raeisi-Dehkordi H, Amiri M, Beigrezaei S, Quezada-Pinedo HG, Khatami F, Alijla F, Steur M, Chatelan A, Voortman T, van der Schouw YT, Franco OH, Muka T. Endogenous Sex Steroid Hormones, Sex Hormone-Binding Globulin, and Risk of All-Cause and Cause-Specific Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies. Journal of Clinical Endocrinology & Metabolism. 2025;110(9):e3131-e3149.