Biomarkers · Endocrine
Thyroxine (Total T4)
U-shaped: both low and high values carry risk. Not measured in our NHANES panel; the curve is synthesised from the published association.
Hazard ratio relative to the curve's reference value, as synthesised from the published association.
Published hazard ratio1.27top vs bottom third (95% CI 1.14–1.42) · NHANES 2001-2012 thyroid profile mortality linkage
Where people sit
Population percentiles (ug/dL) by sex and age band. Cycle or source as recorded in the catalogue.
| Sex | Age | 5th | 25th | Median | 75th | 95th | n | Cycle / source |
|---|---|---|---|---|---|---|---|---|
| All | 20-39 | 4.81 | 6.48 | 7.64 | 8.80 | 10.5 | 5,400 | Peto et al. 2017 (Mort… |
| All | 40-59 | 5.31 | 6.98 | 8.14 | 9.30 | 11.0 | 5,400 | Peto et al. 2017 (Mort… |
| All | 60+ | 5.81 | 7.50 | 8.68 | 9.85 | 11.5 | 5,400 | Peto et al. 2017 (Mort… |
| All | all | 5.31 | 6.98 | 8.14 | 9.30 | 11.0 | 5,400 | Peto et al. 2017 (Mort… |
| Men | all | 5.55 | 7.23 | 8.38 | 9.54 | 11.2 | 5,400 | Peto et al. 2017 (Mort… |
| Women | all | 5.07 | 6.74 | 7.90 | 9.06 | 10.7 | 5,400 | Peto et al. 2017 (Mort… |
Sources
- Hazard curve: Peto et al. 2017 (PMID 28858850) anchor; nhanes_cox_spline
- Peto MV, et al. MortalityPredictors.org: a manually-curated database of published results from longitudinal studies of mortality risk factors. Aging (Albany NY). 2017;9(9):1965-1983.