Biomarkers · Hematology
Transferrin Saturation
U-shaped: both low and high values carry risk. Not measured in our NHANES panel; the curve is synthesised from the published association.
Hazard ratio relative to the curve's reference value, as synthesised from the published association.
Published hazard ratio1.60top vs bottom quarter (95% CI 1.17–2.21) · NHANES I (1971-1974) merged with NHANES I Epidemiologic Followup Study (1992), n=10714 US adults
Where people sit
Population percentiles (%) by sex and age band. Cycle or source as recorded in the catalogue.
| Sex | Age | 5th | 25th | Median | 75th | 95th | n | Cycle / source |
|---|---|---|---|---|---|---|---|---|
| All | 20-39 | 15.2 | 23.9 | 30.0 | 36.1 | 44.8 | 2,580 | 2017-2018 |
| All | 40-59 | 15.2 | 23.9 | 30.0 | 36.1 | 44.8 | 2,550 | 2017-2018 |
| All | 60+ | 15.2 | 23.9 | 30.0 | 36.1 | 44.8 | 2,670 | 2017-2018 |
| All | all | 15.2 | 23.9 | 30.0 | 36.1 | 44.8 | 7,800 | 2017-2018 |
| Men | all | 15.2 | 23.9 | 30.0 | 36.1 | 44.8 | 3,780 | 2017-2018 |
| Women | all | 15.2 | 23.9 | 30.0 | 36.1 | 44.8 | 4,020 | 2017-2018 |
Sources
- Hazard curve: Synthesized from mortality_association (HR=1.6 quartile_extreme); per-SD log(HR)=0.367. Reported as threshold HR=1.6 for all-cause mortality. HR for serum transferrin saturation >55% vs <=55% (clinical iron-overload threshold), adjusted f
- Mainous AG 3rd, Gill JM, Carek PJ. Elevated serum transferrin saturation and mortality. Annals of Family Medicine. 2004;2(2):133-138.