PFLPhysiological Fitness Landscape

Open problems · P3

Informative sampling in clinical lab data

Clinical labs are dense but ordered when something is wrong. Joint models of when a test is taken and what it shows are needed before routine health-system data can be used.

Why it matters

Health-system labs are the only source dense enough to see individual trajectories at scale. Naive analysis of them confuses being tested with being ill.

What exists

  • A planned retrospective analysis with Alberta laboratory data (application in preparation).
  • Population curves to serve as priors.

A first step

Adapt a joint visit-process and outcome model to a simulated health-system schedule and quantify the bias of ignoring the visit process.

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