Explore the landscape · HbA1c × body mass index

HbA1c × body mass index

The low ground sits near HbA1c 5.4% and BMI 27. At normal HbA1c, a BMI of 20 carries more hazard than a BMI of 35 (1.9× against 1.2×), the familiar pattern of illness-related weight loss.

Mortality hazard1.00× reference

HbA1c: 5.5
BMI: 27.9
Within data: yes

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Hazard relative to the reference, by contour band.

Cox model with restricted cubic splines and a HbA1c × BMI interaction (likelihood-ratio p = 0.20), adjusted for age and sex. NHANES 1999–2018 with linked mortality to 2019; 48,298 adults, 6,835 deaths. Hazards are associations: the move button reads the surface at a new position and is not a trial estimate of what treatment would do. The age path joins population medians by age band (NHANES 2017–18), which is cross-sectional and does not follow one person.

How to read it

Colour shows all-cause mortality hazard relative to the reference point, from a Cox model fitted on 48,298 adults with 6,835 deaths. Each contour band is one step on the scale beside the map. Hatched areas hold too few people to estimate.

The interaction test asks whether the two markers combine differently from the sum of their separate effects (likelihood-ratio p = 0.20). Use Copy link to this view to share the exact position you are looking at.

Biomarker pages: Glycated Hemoglobin (HbA1c) · Body Mass Index (BMI).