Explore the landscape · Inflammation (CRP) × albumin

Inflammation (CRP) × albumin

Albumin matters at every level of inflammation: a fall from 45 to 38 g/L raises hazard by 40–75%, most where CRP is low. High CRP adds its own rise on top.

Mortality hazard1.00× reference

CRP: 2.1
Albumin: 42
Within data: yes

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Hazard relative to the reference, by contour band.

Cox model with restricted cubic splines and a CRP × Albumin interaction (likelihood-ratio p = 0.04), adjusted for age and sex. NHANES 1999–2018 with linked mortality to 2019; 38,130 adults, 6,118 deaths. Hazards are associations: the move button reads the surface at a new position and is not a trial estimate of what treatment would do. The age path joins population medians by age band (NHANES 2017–18), which is cross-sectional and does not follow one person.

How to read it

Colour shows all-cause mortality hazard relative to the reference point, from a Cox model fitted on 38,130 adults with 6,118 deaths. Each contour band is one step on the scale beside the map. Hatched areas hold too few people to estimate.

The interaction test asks whether the two markers combine differently from the sum of their separate effects (likelihood-ratio p = 0.04). Use Copy link to this view to share the exact position you are looking at.

Biomarker pages: High-Sensitivity C-Reactive Protein (hs-CRP) · Serum Albumin.